Laptops

A laptop as the name indicates is used as a portable device which is used for lots of applications. A laptop is actually a small version of the desktop computer. It has lot of advantages over the desktop computers the main advantages are ,it can be taken anywhere we want. It emits amount of heat which is very less compared to the desktop systems. Here the Monitor and the CPU unit is joined together. But when it comes to cost of the product the laptops are a bit costlier than the desktops.

Shoulder Stretch

• Raise your arm to shoulder height and bring your arm across the front of your body.
• If using your right arm, your right hand should rest at your left shoulder.
• Take your left arm and place it behind your right elbow. Slowly and gently apply pressure just above your right elbow to feel a stretch in the back of the right shoulder.
• Hold for 30 seconds and then repeat for the other side.

Water is elixir of life

Water is very important for existence of living things. Water is an elixir of life. Without water no one can survive .Our Earth consists 70% of water. It is special for its transparence property. It is used for cooking. According to scientific report we should drink 6 liters of water per day. If we drink lots of water we will be away from diseases.

The deNovo ProteinModeling

Continuous-space models based on all-atom representations lack the ability to find a global free energy minimum of a typical protein in a tractable period of time. The most straightforward solution to this problem is to reduce the large number of degrees of freedom by employing a reduced representation of a protein chain or/and simplified interaction scheme.

• Continuous Space Reduced Models
• High Resolution Lattice Models

Ghajini Movie

This is a tamil movie directed by A.R.Murgadoss,starring Surya sivakumar, Asin,the film was relesed in theseptember 2005,the films running time is 1280 minutes.The main concept of the film is Love and then the short term memory loss of the hero.The films budget was 7.5 crore.The first half of the film shows the Love,the second thing is the act of the villain,then the second half features the revenge of the hero and whether he succeeds in the revenge or not.

Hamstring stretch

Hamstring stretch is done to stretch the hamstring muscles. To do this first lie flat on the ground, lift the left leg up and move it till it perpendicular to the ground and if its difficult u can make use of a towel to be round about the leg and pulled by hands stretch until u can and then leave the left leg and make it rest as in the initial position now repeat the steps with the other leg.

Subcellular Localization Prediction

Subcellular localization can be considered as a type of gene function. Indeed the Gene Ontology organizes terms for describing localization in a DAG named cellular component. Some proteins have a signal peptide typically at its N-terminal region, which are recognized by a transporting protein and later often cleaved off. Therefore a direct way to predict subcellular localization is to recognize these signals.94 Since molecular protein sorting mechanism differs in prokaryotes and eukaryotes, predictionmethods is usually specifically designed for either one of them or for a sub-category, such as plants. PSORT is one of the earliest prediction methods, which uses multiple sequence features including signal peptides, amino acid composition, sequence motifs, and predicted trans-membrane domains in the form of a decision rule or a classifier.95,96 They have an extensive collection of links to prediction methods and related resources at their web site,demonstrate that cellular localization is an evolutionarily conserved property andhomologs tend to occur at the same cellular sites. Proteome Analyst99 obtains annotationscorresponding to homologous sequences detected using BLAST and then uses them withan organism specific Bayesian classifier to classify the query protein to localization sites.Some methods100–102 use SVM to classify proteins across different cellular components based on the frequency of twenty amino acids. The phylogenetic profile can be also used to predict localization.

Alcoholism

Its a disease caused due to consuming alcohol and other alcoholic beverages.When taken in small amounts it causes a feeling of relaxation.But when taken in large amounts it leads to the impairement of speech and muscular coordination.It may also irritate the stomach lining.A very large amount can lead to severe depression of central nervous system and may become fatal.

Gene Ontology

GO consists of hierarchically structured vocabulary divided into three basic subcategories: molecular function, biological process and cellular component. Each term in GO is referred by an identifier of the form GO:xxxxxxx, a subcategory, and an associated textual description for that term. For example, the identifier GO:0019319 is of subcategory biological process and has short description as ‘hexose biosynthetic process’ (Figure). GO organizes the terms in a directed acyclic graph (DAG) structure where terms are associated by is a or part of relationships. The is a classifier represents a subclass relationship where ‘A is a B’ means A is description of B but at higher depth or more narrower description. ‘A part of B’ indicates that whenever A is present it is part of B. A gene can be described as performing one or more molecular functions, being part of one or more biological process and located in one or more cellular components. Another important feature of GO is that it supports association of an evidence code with each annotation indicating the nature of evidence sources that are used to support that annotation. Examples of the evidence codes are IDA (Inferred from Direct Assay), which indicates that a direct assay was carried out to determine the function, and ISS (Inferred from Sequence or Structural Similarity), which clarifies that any analysis based on sequence alignment, structure comparison, or evaluation of sequence features such as composition is performed.